RAPID INFUSION PAPAVERINE HYDROCHLORIDE THERAPY IN SUDDEN HEARING LOSS
Dr. Serdar ENSARİ, Dr. Serdar ÇELİKKANAT, Dr. M. Cem ÖZBEK, Dr. Özel ŞEMİ, Dr. Cafer ÖZDEM
Ankara Numune Hastanesi 2. KBB Kliniği
The etiology, histopathology, short-term and long-term prognosis, and treatment of sudden hearing loss which is an emergency situation, are not well defined in the literature. Since different theories attempt to explain the pathophysiology of sudden deafness many different regimens have been used for the treatment up to now. Between 1991 and 1996, 57 patients suffering from idiopathic sudden sensorineural hearing loss (ISHL) received rapid infusion papaverine hydrochloride therapy. in 11 patients there were no recovery. However 10 patients had slight, 11 patients partial and 25 patients had complete recovery. Patients who were treated Within 7 days had significantly better recovery. Therefore because of the positive effect on recovery, the low incidence of side effects and reliability we concluded to advise keeping papaverine hydrochloride, a selective cerebral vasodilator, in mind for the treatment of ISHL.
Keywords: Sudden sensorineural hearing loss, papaverine hydrochloride
K.B.B. ve Baş Boyun Cerrahisi Dergisi, 3995; 6(2): 55-59