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CASE REPORTS

Neurofibroma in the Nasal Cavity: A Rare Clinical Entity
Nazal Kavite Yerleşimli Nörofibrom: Nadir Bir Klinik Durum
Received Date : 30 May 2021
Accepted Date : 24 Nov 2021
Available Online : 02 Dec 2021
Doi: 10.24179/kbbbbc.2021-84729 - Makale Dili: EN
KBB ve BBC Dergisi. 2022;30(2):103-7
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Most peripheral nerve sheath tumors are benign. Neurofibroma, one of the peripheral nerve sheath tumors, is rarely seen in the nasal cavity. Definitive diagnosis of neurofibroma can be made by histopathological examination of the specimen. A 46-year-old female patient was admitted to Fatih Sultan Mehmet Health Practice and Research Center Ear Nose and Throat clinic with swelling complaints that have been slowly growing at the entrance to the left nasal cavity for a long time. In the examination, approximately 1x1 cm mass was detected under the skin in the left medial crus of the alar cartilage. The patient underwent mass excision from the left nasal passage under local anesthesia. The patient had no postoperative complications. Histopathological examination of the operation material was reported as a neurofibroma. The aim of this case report is discuss case in light of literature in the terms of symptoms, diagnosis and surgical methods.
ÖZET
Periferik sinir kılıfı tümörlerinin çoğu benigndir. Periferik sinir kılıfı tümörlerinden olan nörofibroma nazal kavitede nadiren görülmektedir. Nörofibromun kesin tanısı; spesimenin histopatolojik inceleme sonucuyla konulabilir. 46 yaşında kadın hasta, uzun senelerdir sol nazal kavite girişinde yavaş bir şekilde büyüme gösteren kitle şikayeti ile Fatih Sultan Mehmet Eğitim ve Araştırma Hastanesi Kulak Burun Boğaz polikliniğine başvurdu. Hastanın preoperatif muayenesinde solda alar kartilaj medial yüzü üzerinde cilt altında yaklaşık 1x1 cm boyutlarında kitle tespit edildi. Hastaya lokal anestezi altında sol nazal pasajdan kitle eksizyonu operasyonu yapıldı. Hastanın postoperatif komplikasyonu olmadı. Operasyon materyalinin histopatolojik inceleme sonucu nörofibrom olarak raporlandı. Ameliyat spesmenin histopatolojik sonucu; nörofibrom gelmiştir. Bu bildirinin amacı; olgunun semptom, tanı ve tercih edilecek cerrahi yöntemleri açısından literatür ışığında tartışılmasıdır.
KAYNAKLAR
  1. Canda MS. [Peripheral nerve sheath tumors]. Türkiye Ekopatoloji Dergisi. 2004;10(1-2):65-74. [Link] 
  2. Mondal AR, Rashid MA, Bera SP, Roy S. Neurofibroma of paranasal sinuses - a case report. Indian J Otolaryngol Head Neck Surg. 2004;56(1):40-2. [Crossref]  [PubMed]  [PMC] 
  3. Ohashi R, Wakayama N, Kawamoto M, Tsuchiya S, Okubo K. Solitary nasal schwannoma: Usefulness of CD34 and calretinin staining for distinction from histological mimics. J Nippon Med Sch. 2013;80(4):300-6. [Crossref]  [PubMed] 
  4. Gökçeer T, Yaylaci A, Akkaynak AC, Peker O, Karaaslan O. [Nasal schwannoma: a report of two cases]. Kulak Burun Bogaz Ihtis Derg. 2004;13(1-2):46-50. Turkish. [PubMed] 
  5. Azani AB, Bishop JA, Thompson LD. Sinonasal tract neurofibroma: a clinicopathologic series of 12 cases with a review of the literature. Head Neck Pathol. 2015;9(3):323-33. [Crossref]  [PubMed]  [PMC] 
  6. Sharma DK, Sohal BS, Parmar TL, Arora H. Schwannomas of head and neck and review of literature. Indian J Otolaryngol Head Neck Surg. 2012;64(2): 177-80. [Crossref]  [PubMed]  [PMC] 
  7. Ada E. [Imaging in Diagnosis and Follow-up in Sinonazal Neoplasia]. Trd Sem 2018; 6: 380-95. [Crossref] 
  8. Min HJ, Kim KS. Differential diagnosis between nasal septal schwannoma and nasal septal neurofibroma. J Craniofac Surg. 2017;28(7):1780-3. [Crossref]  [PubMed] 
  9. Biswas D, Mal R. Bilateral solitary maxillary sinus neurofibroma. Ear Nose Throat J. 2010;89(1):E1-2. [Crossref]  [PubMed] 
  10. Rokutanda S, Yamada SI, Kawasaki G, Kawano T, Yanamoto S, Fujita S, et al. Solitary neu rofibroma of the maxillary sinus: report of a case. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2012;24(3):171-4. [Crossref] 
  11. Kuroda N, Kazakov DV, Hes O, Michal M, Goda M, Miyazaki K, et al. Hybrid peripheral nerve sheath tumor of the nasal cavity showing sch wannomatous, neurofibromatous, and perineuriomatous areas. Med Mol Morphol. 2010;43(2): 82-5. [Crossref]  [PubMed]