CASE REPORTS
Brown Tumor as a Cause of Mass in the Oral Cavity
Oral Kavitede Kitle Nedeni Olarak Brown Tümör
Received Date : 20 Dec 2020
Accepted Date : 05 Jan 2021
Available Online : 23 Mar 2021
İrfan KARAa, Alperen VURALb, Seher DARAKCIc, Gülten Benan GÖÇERb, Kerem KÖKOĞLUb, Serap DOĞANd, Ayşa HACIOĞLUe
aKahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları ABD, Kahramanmaraş, TÜRKİYE
bErciyes Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları ABD, Kayseri, TÜRKİYE
cBingöl Devlet Hastanesi, Patoloji Kliniği, Bingöl, TÜRKİYE
dErciyes Üniversitesi Tıp Fakültesi, Radyoloji ABD, Kayseri, TÜRKİYE
eMuş Devlet Hastanesi Endokrinoloji ve Metabolizma Hastalıkları Kliniği, Muş, TÜRKİYE
Doi: 10.24179/kbbbbc.2020-80717 - Makale Dili: TR
KBB ve BBC Dergisi. 2021;29(2):152-8
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Brown tumors (osteitis fibrosa cystica) are non-neoplastic
lesions caused by abnormal bone metabolism due to hyperparathyroidism.
It is often accompanied by secondary hyperparathyroidism, it
is more rare to accompany primary hyperparathyroidism. The Brown
tumor is often seen in the ribs, clavicle and pelvis, but may involve any
bone in the skeletal system, including maxillofacial bones. The
mandible is held more frequently than the maxilla in the chin area. They
are clinically smooth, soft and bone destructive lesions. These lesions
may mimic malignancy clinically and radiologically. While there is a
common view of the intervention of the parathyroid glands that cause
Brown tumor treatment, there is no consensus regarding the intervention
for Brown tumor. In this article, four Brown tumor cases secondary
to primary hyperparathyroidism that cause mass lesion in the oral cavity
and our approach to cases are discussed in the light of the literature.
Keywords: Osteitis fibrosa cystica; primer hyperparathyroidism; mouth; benign neoplasm
ÖZET
Brown tümör (osteitis fibroza sistika), hiperparatiroidiye bağlı
anormal kemik metabolizması sonucu oluşan nonneoplastik lezyonlardır.
Sıklıkla sekonder hiperparatiroidiye eşlik etmektedir, primer hiperparatiroidili
hastalarda daha nadir görülmektedir. Brown tümör
sıklıkla kostalar, klavikula ve pelviste görülmekle birlikte maksillofasiyal
kemikler dâhil iskelet sistemindeki her kemiği tutabilir. Çene bölgesinde
mandibula maksilladan daha sık tutulmaktadır. Klinik olarak
düzgün yüzeyli, yumuşak ve kemik destrüksiyonu yapan lezyonlardır.
Bu lezyonlar, klinik ve radyolojik olarak maligniteyi taklit edebilir.
Brown tümör tedavisinde hastalığa sebep olan paratiroid bezlerine yönelik
cerrahi müdahale konusunda ortak görüş varken, Brown tümöre
yönelik müdahale konusunda fikir birliği yoktur. Bu yazıda, oral kavitede
kitle lezyonu yapan primer hiperparatiroidiye sekonder gelişen 4
Brown tümörlü olgu ve olgulara yaklaşımımız literatür eşliğinde tartışılmıştır.
Anahtar Kelimeler: Osteitis fibroza sistika; primer hiperparatiroidi; ağız; benign neoplazm
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