ORIGINAL RESEARCH
Complete Blood Count Parameters in Recurrent Pediatric Idiopathic Epistaxis
Rekürren İdiyopatik Pediatrik Epistaksiste Tam Kan Sayımı Parametrelerinin yeri
Received Date : 19 Aug 2019
Accepted Date : 22 Oct 2019
Available Online : 19 Nov 2019
M. Volkan AKDOĞANa, Suna TANRIKULUa, Seda BABAKURBANa, Mahmut GÖKDEMİRb
aDepartment of Otolaryngology,
bDivision of Pediatric Cardiology,
Başkent University Faculty of Medicine, Ankara, TURKEY
Doi: 10.24179/kbbbbc.2019-71049 - Makale Dili: EN
KBB ve BBC Dergisi 2019;27(3):97-103
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: The aim of this study was to investigate the relationship between complete
blood cell count (CBC) parameters and pediatric recurrent idiopathic epistaxis. Material and
Methods: The patient records of the children with epistaxis were retrospectively analyzed. The
records of the patients with recurrent idiopathic epistaxis were included. Compete blood count results
of the patients at of least two visits for epistaxis were retrieved from the hospital records.
Mean platelet volume (MPV), red blood cell distribution width (RDW), platelet, hemoglobin,
hematocrit, lympocyte, leucocyte, neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte
ratio (PLR) levels of these patients were compared with age-matched and gender-matched
controls. Results: A total of 153 patients had at least two visits with epistaxis and 107 of these were
diagnosed with recurrent idiopathic epistaxis patients. There was no statistical difference in terms
of age and gender between the groups. MPV, RDW, lympocyte levels were higher and platelet, hemoglobin,
hematocrit, leucocyte, NLR and PLR levels were lower in recurrent idiopathic epistaxis
patients. No statistically significant difference was detected between the groups according to
the permutational non-parametric MANOVA (p>0.05). Conclusion: Complete blood count is one
of the most common laboratory test for evaluation of epistaxis in children. Although MPV, RDW,
NLR and PLR are easily measured as a part of the CBC, their importance in epistaxis is not adequately
presented. MPV, RDW, NLR and PLR have been identified as markers of inflammation and
associated with an ample amount of diseases. However in this study we have concluded that there
was no association between CBC parameters and recurrent pediatric idiopathic epistaxis.
Keywords: Epistaxis; children; complete blood cell count; mean platelet volume
ÖZET
Amaç: Bu çalışmanın amacı, tam kan sayımı (TKS) parametreleri ile pediatrik rekürren
idiyopatik epistaksis arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntemler: Epistaksisi olan çocukların
hasta kayıtları retrospektif olarak incelendi. Rekürren idiyopatik epistaksisi olan hastalar
çalışmaya dahil edildi. En az iki kez burun kanaması nedeniyle başvuran hastaların TKS
sonuçları, hastane kayıtlarından elde edildi. Bu hastaların ortalama trombosit hacmi (OTH), eritrosit
dağılım genişliği (EDG), trombosit, hemoglobin, hematokrit, lenfosit, lökosit, nötrofil/lenfosit
oranı (NLO) ve trombosit/lenfosit oranı (TLO) düzeyleri benzer yaş ve cinsiyetteki sağlıklı
bireylerle karşılaştırıldı. Bulgular: Toplamda 153 hastanın epistaksis tanısı ile birden fazla başvurusu
vardı. Bunlardan 107’si rekürren idiyopatik epistaksis tanısı almıştı. Gruplar arasında yaş
ve cinsiyet açısından istatistiksel fark yoktu. Rekürren idiyopatik epistaksis hastalarında OTH,
EDG, lenfosit düzeyleri yüksek, trombosit, hemoglobin, hematokrit, lökosit, NLO ve TLO düzeyleri
düşüktü. Ancak gruplar arasında istatistiksel olarak anlamlı bir fark yoktu (p>0,05). Sonuç:
Tam kan sayımı, çocuklarda epistaksinin değerlendirilmesinde en yaygın kullanılan laboratuar
testlerinden biridir. Her ne kadar OTH, EDG, NLO ve TLO, TKS'nin bir parçası olarak kolayca
ölçülse de, burun kanamasındaki önemi yeterince ortaya konmamıştır. OTH, EDG, NLO ve TLO,
inflamasyon belirtiçleri olarak tanımlanmıştır ve birçok hastalıkla ilişkilendirilmiştir. Ancak bu
çalışmada TKS parametreleri ile rekürren pediatrik idiyopatik epistaksis arasında bir ilişki olmadığı
sonucuna varılmıştır.
Anahtar Kelimeler: Epistaksis; çocuk; tam kan sayımı; ortalama trombosit hacmi
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