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ORIGINAL RESEARCH

Effect of Dexamethasone Administration to the Fenestra during Stapedotomy on Postoperative Dizziness
Stapes Cerrahisi Sırasında Fenestra Üzerine Deksametazon Uygulamasının Postoperatif Baş Dönmesi Üzerine Etkisi
Received Date : 03 Aug 2021
Accepted Date : 20 Oct 2021
Available Online : 02 Nov 2021
Doi: 10.24179/kbbbbc.2021-85624 - Makale Dili: EN
KBB ve BBC Dergisi. 2021;29(4):264-70
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: To evaluate the effect of dexamethasone administration to the fenestra during stapedotomy on early postoperative dizziness. Material and Methods: Of all 85 patients, who underwent stapedotomy for otosclerosis, were divided into 2 groups according to whether dexamethasone was administered immediately after fenestra was opened during surgery. In the dexamethasone group, 4 drops (0.8 mg/0.2 mL) of dexamethasone phosphate were administered to fenestra using a 21-gauge injector immediately after stapedotomy during the surgery. These 2 groups were compared in terms of the severity of postoperative dizziness and its effect on quality of life, hearing thresholds, length of stay in the hospital and drugs used for dizziness. Results: The postoperative air-bone gap was 14±6 decibel in both the dexamethasone and control groups. The severity of dizziness on the day of the surgery was 4.68/10 points (range, 2-9) and 5.24/10 points (range, 2-8) in the dexamethasone and control groups, respectively (p=0.048). On the day of discharge, the severity of dizziness was 3.1/10 points (range, 0-9) and 3.78/10 points (range, 1-6) in the dexamethasone and control groups, respectively (p=0.008). The postoperative use of metoclopramide HCl was 0.33±0.764 units and 0.87±1.07 units in the dexamethasone and control groups, respectively (p=0.003). Conclusion: The results suggest that dexamethasone administration to the fenestra during otosclerosis surgery may reduce the severity of dizziness and the frequency of antiemetic drug use in the early period after stapedotomy while it has no effect on the hearing thresholds and dizziness in the long term period.
ÖZET
Amaç: Stapedotomi sırasında fenestraya deksametazon uygulamasının erken postoperatif baş dönmesi üzerine etkisini değerlendirmek. Gereç ve Yöntemler: Otoskleroz nedeniyle stapedotomi uygulanan toplam 85 hasta, ameliyat sırasında fenestra açıldıktan hemen sonra deksametazon uygulanıp uygulanmamasına göre 2 gruba ayrıldı. Deksamatazon grubunda, 4 damla (0,8 mg/0,2 mL) deksamatazon fosfat operasyonda stapedotomi hemen sonrası fenestra üzerine 21-gauge enjektör ucundan damlatılmıştır. Bu 2 grup, ameliyat sonrası baş dönmesinin şiddeti ve yaşam kalitesine etkisi, işitme eşikleri, hastanede kalış süresi ve baş dönmesi için kullanılan ilaçlar açısından karşılaştırıldı. Bulgular: Ameliyat sonrası hava-kemik aralığı hem deksametazon hem de kontrol gruplarında 14±6 desibel idi. Ameliyat sonrası aynı gün, baş dönmesinin şiddeti deksametazon ve kontrol gruplarında sırasıyla 4,68/10 puan (dağılım 2-9) ve 5,24/10 puan (dağılım 2-8) idi (p=0,048). Taburculuk gününde, baş dönmesi şiddeti deksametazon ve kontrol gruplarında sırasıyla 3,1/10 puan (dağılım, 0-9) ve 3,78/10 puan (dağılım, 1-6) idi (p=0,008). Postoperatif metoklopramid HCl kullanımı deksametazon ve kontrol gruplarında sırasıyla 0,33±0,764 ünite ve 0,87±1,07 ünite idi (p=0,003). Sonuç: Sonuçlar otoskleroz cerrahisi sırasında fenestraya deksametazon uygulanmasının stapedotomi sonrası erken dönemde baş dönmesi şiddetini ve antiemetik ilaç kullanım sıklığını azaltabileceğini bunun yanında uzun dönemde işitme eşikleri ve baş dönmesi üzerinde herhangi bir etki oluşturmayacağını düşündürmektedir.
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