ORIGINAL RESEARCH
Evaluation of Patients with Allergic Rhinitis in Alanya Province
Alanya Bölgesindeki Alerjik Rinit Hastalarının Değerlendirilmesi
Received Date : 19 Nov 2019
Accepted Date : 12 Feb 2020
Available Online : 17 Mar 2020
Kübra ÇOBANa, M. Volkan AKDOĞANb, Işılay ÖZc
aBaşkent Üniversitesi Alanya Uygulama ve Araştırma Merkezi, Kulak Burun Boğaz Hastalıkları ABD, Antalya, Türkiye
bBaşkent Üniversitesi Konya Araştırma ve Uygulama Merkezi, Kulak Burun Boğaz Hastalıkları ABD, Konya, Türkiye
cBaşkent Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları ABD, Ankara, Türkiye
Doi: 10.24179/kbbbbc.2019-72441 - Makale Dili: TR
KBB ve BBC Dergisi. 2020;28(3):261-7
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: In this study, the characteristics of patients
diagnosed as allergic rhinitis in Alanya region are presented. The aim
of this study was to update our knowledge of allergic rhinitis and to investigate
and reveal regional differences in allergic rhinitis patients.
Material and Methods: Patients who were diagnosed as allergic rhinitis
by history, physical examination, biochemistry and skin prick tests
between September 2018-September 2019 at Baskent University
Alanya Research and Application Hospital were included in the study.
Results: 166 patients were included in the study. 97 (63.25%) of the patients
were female and 69 (36.75%) were male. The mean age was
41.25±15.17 years. The age distribution was between 6-80 years. Pediatric
patients accounted for 4.8% of our cases. Perenial allergic rhinitis
(PAR) was diagnosed in 83.23% and seasonal allergic rhinitis
(MAR) in 16.77%. Serum total immunglobulin E (IgE) levels were
93.80±134.17 in the MAR group and 226.56±380.19 in the PAR group.
There was a significant difference in IgE levels between the two groups
(p=0.003). The most common presenting complaint was nasal obstruction-
respiratory distress (25.1%). In 13.8% of the cases, there was another
concomitant allergic disease. Additional diseases were observed
more frequently in PAR group compared to MAR group (p<0.05). Skin
prick test revealed a single allergen sensitivity of 7.8% (n=13) and multiple
allergen sensitivity of 92.2% (n=153). The mean number of positive
allergens in PAR patients was 6.07±3.8 and in MAR patients was
3±1.9. The difference between the two groups was statistically significant
(p<0.01). The most common positivity in skin prick test was found
against house mites Dermatophagoides pteronyssinus (52.8%) and Dermatophagoides
farinae (52.1%). Conclusion: With this and similar
studies, it will be possible to increase awareness of allergic rhinitis and
to determine the effects of geographic regional variables on the course
of the disease in allergic rhinitis patients.
Keywords: Allergic rhinitis; seasonal allergic rhinitis; perenial allergic rhinitis
ÖZET
Amaç: Alanya Bölgesi’nde alerjik rinit tanısı konulan hastaların
özellikleri sunulmuştur. Bu çalışma ile alerjik rinit hastalığı ile ilişkili
bilgilerimizin güncellenmesi, alerjik rinit hastalarındaki bölgesel
farklılıkların araştırılması ve ortaya konulması amaçlanmıştır. Gereç
ve Yöntemler: Eylül 2018-Eylül 2019 tarihleri arasında, Başkent Üniversitesi
Alanya Araştırma ve Uygulama Hastanesinde öykü, fizik muayene,
biyokimya ve deri prick testleri ile alerjik rinit tanısı konan
hastalar çalışmaya dâhil edildi. Bulgular: Çalışmaya 166 hasta dâhil
edildi. Hastaların 97 (%58,4)’si kadın, 69 (%41,5)’u erkekti. Ortalama
yaş 41,25±15,17 olarak belirlendi. Yaş dağılımı 6-80 yaş arasında idi.
Pediatrik hastalar vakalarımızın %4,8’ini oluşturmaktaydı. Hastaların
%83,23’üne perenial alerjik rinit (PAR), %16,77’sine mevsimsel alerjik
rinit (MAR) tanısı konuldu. Serum total immünglobulin E (IgE) düzeyleri
ortalaması MAR tanılı grupta 93,80±134,17 iken, PAR tanılı
grupta 226,56±380,19 idi. İki grup arasında IgE düzeyi açısından anlamlı
farklılık tespit edildi (p=0,003). En sık başvuru şikâyeti burun tıkanıklığı-
solunum sıkıntısı (%25,1) idi. Vakaların %13,8’inde eşlik
eden başka bir alerjik hastalık bulunmaktaydı. Ek hastalıkların PAR
grubunda, MAR grubuna kıyasla istatistiksel olarak daha sık gözlendiği
tespit edildi (p<0,05). Deri prick testinde tek bir alerjen duyarlılığı
%7,8 (n=13), çoklu alerjen duyarlılığı %92,2 (n=153) olarak tespit
edildi. PAR hastalarında ortalama pozitif alerjen sayısı 6,07±3,8, MAR
hastalarında ise 3±1,9 olarak belirlendi. İki grup arasındaki fark istatistiksel
olarak anlamlı bulundu (p<0,01). Deri prick testinde en sık pozitiflik
ev akarları olan Dermatophagoides pteronyssinus (%52,8) ve
Dermatophagoides farinae’ye (%52,1) karşı tespit edildi. Sonuç: Bu ve
benzeri çalışmalar ile çok çeşitli uzmanlık dallarında görev yapan hekimlerin
alerjik rinit ile ilgili farkındalığını artırmak ve alerjik rinit hastalarında,
coğrafi bölgesel değişkenlerin hastalığın seyri üzerine olan
etkilerini belirlemek mümkün olabilecektir.
Anahtar Kelimeler: Alerjik rinit; mevsimsel alerjik rinit; perenial alerjik rinit
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