ORIGINAL RESEARCH
Evaluation of Peripheral Arterial Disease in Patients with Tinnitus Using the Ankle Brachial Index
Tinnituslu Hastalarda Periferik Arter Hastalığının Ayak Bileği Kolİndeksi Kullanılarak Değerlendirilmesi
Received Date : 04 Sep 2021
Accepted Date : 01 Dec 2021
Available Online : 07 Dec 2021
Sermin KİBAR ŞAYANa, Ayça ÖZBAL KOÇb, Görkem KANARc, Emre ÖZKERd
aClinic of Otorhinolaryngology, Head and Neck Surgery, Van Training and Research Hospital, Van, TURKEY
bDepartment of Otorhinolaryngology, Head and Neck Surgery, BaÅŸkent University Ä°stanbul Medical Research and Practice Center, Ä°stanbul, TURKEY
cClinic of Cardiology Surgery, Van Training and Research Hospital, Van, TURKEY
dDepartment of Cardiology Surgery, BaÅŸkent University Ä°stanbul Medical Research and Practice Center, Ä°stanbul, TURKEY
Doi: 10.24179/kbbbbc.2021-86073 - Makale Dili: EN
KBB ve BBC Dergisi. 2022;30(1):7-11
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: Tinnitus is sometimes the first manifestation
of atherosclerosis. The ankle-brachial index is reported to be a good
marker of atherosclerosis and is indicative of peripheral arterial damage.
Material and Methods: It is a non-invasive test that can be easily
applied in the outpatient clinic. We investigated the association of
peripheral arterial disease in patients with nonpulsatile tinnitus using the
ankle-brachial index. This study demonstrates the role of atherosclerosis
in these patients. We evaluated 25 patients who had no hearing loss
with nonpulsatile tinnitus and a control group of 15 patients who did not
have any tinnitus symptoms. The mean age of all of the patients was
36±12 years. All patients underwent clinical evaluations including a
thorough medical and otologic history, micro-otoscopy, complete blood
count, clinical biochemical analysis, and pure tone and speech audiometry.
Further investigations included magnetic resonance imaging
of the internal acoustic canal, and Doppler ultrasound of the carotid and
vertebral arteries. Results: Patients with an ankle-brachial index <0.9
were accepted as having peripheral arterial occlusive disease. The
Mann-Whitney U test showed that the ankle-brachial index was significantly
lower in patients with tinnitus (p=0.02). Conclusion: This
study shows that peripheral arterial disease is more common in patients
with nonpulsatile tinnitus than in controls without tinnitus. Our findings
support the view that atherosclerosis plays an important role in the
cause of nonpulsatile tinnitus.
Keywords: Tinnutus; atherosclerosis; carotid artery disease; ankle-brachial index
ÖZET
Amaç: Tinnitus bazen aterosklerozun ilk belirtisidir. Ayak bileği-
kol indeksinin aterosklerozun iyi bir belirteci olduÄŸu ve periferik
arter hasarının göstergesi olduğu bildirilmektedir. Gereç ve Yöntemler:
Poliklinikte rahatlıkla uygulanabilen noninvaziv bir testtir. Ayak
bileÄŸi-kol indeksini kullanarak nonpulsatil tinnituslu hastalarda, periferik
arter hastalığı ilişkisini araştırdık. Bu çalışma, bu hastalarda aterosklerozun
rolünü göstermektedir. Nonpulsatil tinnituslu işitme kaybı
olmayan 25 hastayı ve tinnitus semptomu olmayan 15 kontrol grubunu
değerlendirdik. Tüm hastaların yaş ortalaması 36±12 yıl idi. Tüm hastalara
kapsamlı bir tıbbi ve otolojik öykü, mikro-otoskopi, tam kan sayımı,
klinik biyokimyasal analiz, saf ses ve konuşma odyometrisi dâhil
klinik değerlendirmeler yapıldı. Daha ileri araştırmalar, dahili akustik
kanalın manyetik rezonans görüntülemesini, karotis ve vertebral arterlerin
Doppler ultrasonunu içeriyordu. Bulgular: Ayak bileği-kol indeksi
<0,9 olan hastaların periferik arter tıkayıcı hastalığı olduğu kabul
edildi. Mann-Whitney U testi, kulak çınlaması olan hastalarda ayak bileği-
kol indeksinin anlamlı olarak daha düşük olduğunu gösterdi
(p=0,02). Sonuç: Bu çalışma, periferik arter hastalığının, nonpulsatil
tinnituslu hastalarda tinnitussuz kontrollere göre daha yaygın olduğunu
göstermektedir. Bulgularımız, aterosklerozun nonpulsatil tinnitusun nedeninde
önemli bir rol oynadığı görüşünü desteklemektedir.
Anahtar Kelimeler: İnnitus; ateroskleroz; karotis arter hastalıkları; ayak bileği-kol indeksi
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