ORIGINAL RESEARCH
Evaluation of the Effect of Behçet's Disease on Vestibulo-Ocular Reflex with Video Head Impulse Test
Behçet Hastalığının Vestibulo-Oküler Refleks Üzerine Etkisinin Video Baş Savurma Testi ile Değerlendirilmesi
Received Date : 26 Dec 2019
Accepted Date : 26 Feb 2020
Available Online : 12 Mar 2020
Belgin TUTARa, Güler BERKİTENa, Semih KARAKETİRa, Onur AKANb, Ömür Biltekin TUNAa, Yavuz UYARa
aİstanbul Okmeydanı Training and Research Hospital, Clinic of Ear Nose Throat and Head and Neck Section, İstanbul, TURKEY
bİstanbul Okmeydanı Training and Research Hospital, Clinic of Neurology, İstanbul, TURKEY
Doi: 10.24179/kbbbbc.2019-73123 - Makale Dili: EN
KBB ve BBC Dergisi. 2020;28(2):110-6
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: Behçet's disease (BD) is characterized by recurrent
oral and genital ulcers, uveitis and vasculitis throughout the
body. There are not many studies in the literature on the involvement
of the vestibular system in BD. Our aim is to evaluate the vestibular
system in Behçet's patients and to determine the clinical importance of
video head impulse test (vHIT). Material and Methods: Twenty patients
(11 females and nine males) with BD and 15 healthy volunteers
(seven females and eight males) were included in the study. Pure tone
audiometry (PTA), videonystagmography (VNG), dizziness handicap
inventory (DHI) and vHIT tests were administered to all individuals.
Data were evaluated by statistical methods. Results: The mean age of
the patients with BD was 44±11.2 years, and the mean age of the
healthy volunteers was 42±13.3 years. The DHI scores of the patient
group were higher than the control group. Results of vHIT showed significantly
lower VOR gain in the left lateral, right, and left posterior
semicircular canals in the BD group compared to the control group.
Nine (45%) of the BD patients had overt saccade, but none had covert
saccade. Overt and covert saccade were not observed in the healthy volunteers.
Conclusion: vHIT is a fast and accurate test that can be used
to evaluate the vestibular system in patients with BD.
Keywords: Behçet’s disease; vestibulo-ocular reflex; video head impulse test; oral ulcers; genital ulcers; vasculitis
ÖZET
Amaç: Behçet hastalığı (BD), vücutta tekrarlayan oral ve genital
ülserler, üveit ve vaskülit ile karakterizedir. Literatürde vestibüler
sistemin BD'ye katılımı ile ilgili çok fazla çalışma yoktur. Amacımız
Behçet hastalarında vestibüler sistemi değerlendirmek ve video baş savurma
testinin (vHIT) klinik önemini belirlemektir. Gereç ve Yöntemler:
Yirmi iki hasta (11 kadın ve 9 erkek) BD ve 15 sağlıklı gönüllü
(7 kadın ve 8 erkek) çalışmaya dahil edildi. Tüm bireylere saf ton odyometrisi
(PTA), videonistagmografi (VNG), baş dönmesi handikap
envanteri (DHI) ve vHIT testleri uygulandı. Veriler istatistiksel yöntemlerle
değerlendirildi. Bulgular: Behçet Hastalığı olanların yaş ortalaması
44±11,2, sağlıklı gönüllülerin yaş ortalaması 42±13,3 idi.
Hasta grubunun DHI skorları kontrol grubundan daha yüksekti. vHIT
sonuçları BD grubunda sol lateral, sağ ve sol arka semisirküler kanallarda
kontrol grubuna göre anlamlı derecede düşük vestibüler oküler
refleks (VOR) artışı gösterdi. Behçet hastalarının 9 (%45)’unda açık
seğirme vardı, ancak hiçbirinde örtülü seğirme yoktu. Sağlıklı gönüllülerde
açık ve örtülü seğirme görülmedi. Behçetli hastalarda VOR'un
etkilendiği bulundu. Sonuç: vHIT, BD'li hastalarda vestibüler sistemi
değerlendirmek için kullanılabilecek kolay, hızlı ve güvenilir bir testtir.
Anahtar Kelimeler: Behçet hastalığı; vestibülo-oküler refleks; video baş savurma testi; oral ülserler; genital ülserler; vaskülit
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