ORIGINAL RESEARCH
Evaluation of the Effect of the İnferior Turbinate Hypertrophy on the Mean Platelet Volume
Alt Konka Hipertrofisinin Ortalama Trombosit Hacmi Üzerine Etkisinin Değerlendirilmesi
Received Date : 08 Sep 2020
Accepted Date : 16 Dec 2020
Available Online : 17 Mar 2021
Ender ŞAHİNa, Yunus KANTEKİNb, Ceyhun CENGİZa, Hakan DAĞISTANa,
İlknur HABERAL CANa
aYozgat Bozok Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları ABD, Yozgat, TÜRKİYE bKayseri Şehir Hastanesi, Kulak Burun Boğaz Kliniği, Kayseri, TÜRKİYE
Doi: 10.24179/kbbbbc.2020-78810 - Makale Dili: TR
KBB ve BBC Dergisi. 2021;29(2):77-80
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: Inferior turbinate hypertrophy (ITH) is one of
the common causes of nasal obstruction. It is known that nasal obstruction
is associated with chronic hypoxia. The mean platelet volume
(MPV) value increases in conditions that cause chronic hypoxia. The
aim of this study is to investigate the effect of inferior turbinate hypertrophy
on MPV value. Material and Methods: Our study included 80
patients with ITH who applied to the Otorhinolaryngology (ENT) outpatient
clinic between August 2018 and March 2019, as well as 50 age
and sex matched healthy control subjects. The MPV values measured
in the blood samples of the study and control groups were compared.
SPSS 21.0 version statistics program (SPSS for Windows Version 21.0,
SPSS Inc, Chicago, IL, ABD) was used to analyze the data. Results:
There was no statistically significant difference between the groups in
terms of age and gender (p=0.532, p=0.911 respectively). The mean
MPV values in the ITH and control groups were 10.52±0.79 and
9.75±0.62 respectively. The mean MPV value of the ITH group was
significantly higher than that of the control group (p<0,001). Conclusion:
According to the results of our study, MPV values of patients with
ITH are significantly higher than those without ITH. Further studies
are needed to determine the efficacy of ITH treatments on MPV.
Keywords: Nasal obstruction; hypoxia; mean platelet volume; inferior turbinate hypertrophy
ÖZET
Amaç: Alt konka hipertrofisi (AKH), sık görülen nazal obstrüksiyon
sebeplerinden biridir. Nazal obstrüksiyonun, kronik hipoksi
ile ilişkisi bilinmektedir. Ortalama trombosit hacmi (OTH) değeri, kronik
hipoksi oluşturan durumlarda yükselmektedir. Bu çalışmanın amacı,
alt AKH’nin OTH değeri üzerine etkisinin incelenmesidir. Gereç ve
Yöntemler: Çalışmamıza, Ağustos 2018 ve Mart 2019 tarihleri arasında
kulak burun boğaz polikliniğine burun tıkanıklığı nedeniyle başvuran
ve AKH tespit edilen 80 hasta ile yaş ve cinsiyet olarak benzer
50 sağlıklı kişi dâhil edilmiştir. Hasta ve kontrol grubuna ait kan örneklerinde
OTH değerleri ölçülerek karşılaştırma yapılmıştır. Verilerin
analizi için SPSS istatistik programı (SPSS for Windows Version 21.0,
SPSS Inc, Chicago, IL, ABD) kullanılmıştır. Bulgular: Gruplar arasında
yaş ve cinsiyet bakımından istatistiksel olarak anlamlı fark yoktu
(sırasıyla p=0,532, p=0,911). Hasta grubunda ortalama OTH değeri,
10,52±0,79; kontrol grubunda ortalama OTH değeri, 9,75±0,62 olarak
bulundu. AKH grubunun ortalama OTH değeri kontrol grubuna göre
istatistiksel olarak anlamlı derecede daha yüksekti (p<0,001). Sonuç:
Çalışmamızın sonuçları, AKH olan hastaların OTH değerlerinin sağlıklı
kontrol grubuna göre anlamlı derecede yüksek olduğunu göstermiştir.
AKH’ye yönelik yapılacak tedavilerin OTH üzerine etkisini
inceleyecek çalışmalar yapılmasına ihtiyaç vardır.
Anahtar Kelimeler: Burun tıkanıklığı; hipoksi; ortalama trombosit hacmi; alt konka hipertrofisi
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