CASE REPORTS
Malakoplakia of the Neck: A Mass Mimicking a Malignancy on Positron Emission Tomography/Computed Tomography
Boyunda Malakoplaki: Pozitron Emisyon Tomografi/ Bilgisayarlı Tomografide Maligniteyi Taklit Eden Bir Kitle
Received Date : 10 May 2022
Accepted Date : 07 Oct 2022
Available Online : 24 Oct 2022
Kerimcan ÇAKICIa, Ozan GÖKDOĞANa, Mahmut DEMİRTAŞa, Serkan Yaşar ÇELİKb,
İbrahim Önder YENİÇERİc, Harun ÜÇÜNCÜa
aDepartment of Otolaryngology, Muğla Sıtkı Koçman University Faculty of Medicine, Muğla, Türkiye
bDepartment of Pathology, Muğla Sıtkı Koçman University Faculty of Medicine, Muğla, Türkiye
cDepartment of Radiology Muğla Sıtkı Koçman University Faculty of Medicine, Muğla, Türkiye
Doi: 10.24179/kbbbbc.2021-87667 - Makale Dili: EN
KBB ve BBC Dergisi. 2023;31(1):64-8
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
In the head-neck region, experiencing infectious, inflammatory,
and malignant masses is a common fact. However, some
pathologies are rarely seen in the head and neck area, and one of them
is malakoplakia. Malakoplakia is generally a slow-growing benign
tumor in the urogenital region. Diagnosis is made microscopically with
the appearance of Michaelis-Guttman bodies. This case report presents
a 32-year-old patient with a history of early-stage tongue squamous cell
cancer. In the routine follow-up of the patient, a mass with similar features
to malignancy and a definitive pathological diagnosis of malakoplakia
was detected. In this case report, the characteristics of the
patient and the mass are discussed comprehensively.
Keywords: Malakoplakia; head and neck neoplasms; positron emission tomography/ computed tomography
ÖZET
Baş boyun bölgesinde enfeksiyöz, inflamatuar ve malign kitleler
sıklıkla görülmektedir. Ancak bazı patolojiler baş boyun bölgesinde
çok nadir görülür. Malakoplaki, genellikle ürogenital bölgede yavaş
büyüyen iyi huylu bir tümördür. Michaelis-Guttman cisimlerinin
görünümü ile mikroskobik olarak tanı konur. Bu vakada, erken evre dil
skuamöz hücreli kanser öyküsü olan 32 yaşındaki bir hasta
sunulmaktadır. Hastanın rutin takiplerinde malignite ile benzer özellikler
gösteren, kesin patolojik tanısı malakoplaki olan bir kitle
saptanmıştır. Bu olgu sunumunda hastanın ve kitlenin özellikleri
tartışılmıştır.
Anahtar Kelimeler: Malakoplaki; baş ve boyun neoplazileri; pozitron emisyon tomografisi/ bilgisayarlı tomografi
KAYNAKLAR
- Samian C, Ghaffar S, Nandapalan V, Santosh S. Malakoplakia of the parotid gland: a case report and review of localised malakoplakia of the head and neck. Ann R Coll Surg Engl. 2019;101(5):309-12. [Crossref] [PubMed] [PMC]
- van Furth R, van't Wout JW, Wertheimer PA, Zwartendijk J. Ciprofloxacin for treatment of malakoplakia. Lancet. 1992;339(8786):148-9. [Crossref] [PubMed]
- Coates M, Del Pero MM, Nassif R. A case of cutaneous malakoplakia in the head and neck region and review of the literature. Head Neck Pathol. 2016;10(4):444-50. [Crossref] [PubMed] [PMC]
- Long JP Jr, Althausen AF. Malacoplakia: a 25-year experience with a review of the literature. J Urol. 1989;141(6):1328-31. [Crossref] [PubMed]
- Abdou NI, NaPombejara C, Sagawa A, Ragland C, Stechschulte DJ, Nilsson U, et al. Malakoplakia: evidence for monocyte lysosomal abnormality correctable by cholinergic agonist in vitro and in vivo. N Engl J Med. 1977;297(26):1413-9. [Crossref] [PubMed]
- Diapera MJ, Lozon CL, Thompson LDR. Malacoplakia of the tongue: a case report and clinicopathologic review of 6 cases. Am J Otolaryngol-Head Neck Med Surg. 2009;30(2):101-5. [Crossref] [PubMed]
- Omami G, Tamimi D, Branstetter BF. Basic principles and applications of (18)F-FDG-PET/CT in oral and maxillofacial imaging: a pictorial essay. Imaging Sci Dent. 2014;44(4):325-32. [Crossref] [PubMed] [PMC]
- Vaidyanathan S, Patel CN, Scarsbrook AF, Chowdhury FU. FDG PET/CT in infection and inflammation--current and emerging clinical applications. Clin Radiol. 2015;70(7):787-800. [Crossref] [PubMed]
- Goel D, Pradhan D, Tiwary A. Fluorodeoxyglucose avid malakoplakia of the laryngohypopharynx masquerading as malignant tumor: a pathological enigma and clinical dilemma. Indian J Pathol Microbiol. 2018;61(2):298-9. [Crossref] [PubMed]
- Kradin RL, Sheldon TA, Nielsen P, Selig M, Hunt J. Malacoplakia of the tongue complicating the site of irradiation for squamous cell carcinoma with review of the literature. Ann Diagn Pathol. 2012;16(3):214-8. [Crossref] [PubMed]
- Lewis CM, Resto VA, Wu D, Goguen L. Pathology quiz case 2. Diagnosis: malakoplakia of the left tongue base. Arch Otolaryngol Head Neck Surg. 2006;132(10):1157, 9. [Crossref] [PubMed]
- Schmerber S, Lantuejoul S, Lavieille JP, Reyt E. Malakoplakia of the neck. Arch Otolaryngol Head Neck Surg. 2003;129(11):1240-2. [Crossref] [PubMed]
- van der Voort HJ, ten Velden JA, Wassenaar RP, Silberbusch J. Malacoplakia. Two case reports and a comparison of treatment modalities based on a literature review. Arch Intern Med. 1996;156(5):577-83. [Crossref] [PubMed]