CASE REPORTS
Neurofibroma in the Nasal Cavity: A Rare Clinical Entity
Nazal Kavite Yerleşimli Nörofibrom: Nadir Bir Klinik Durum
Received Date : 30 May 2021
Accepted Date : 24 Nov 2021
Available Online : 02 Dec 2021
Serhan KESKİNa, Tuğba ASLAN DÜNDARa, Emrah TEKDEMİRa, Arzu TATLIPINARa,
Adnan SOMAYb
aClinic of Otorhinolaryngology, Head and Neck Surgery, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, TURKEY
bClinic of Pathology, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, TURKEY
Doi: 10.24179/kbbbbc.2021-84729 - Makale Dili: EN
KBB ve BBC Dergisi. 2022;30(2):103-7
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Most peripheral nerve sheath tumors are benign. Neurofibroma,
one of the peripheral nerve sheath tumors, is rarely seen in
the nasal cavity. Definitive diagnosis of neurofibroma can be made by
histopathological examination of the specimen. A 46-year-old female
patient was admitted to Fatih Sultan Mehmet Health Practice and Research
Center Ear Nose and Throat clinic with swelling complaints that
have been slowly growing at the entrance to the left nasal cavity for a
long time. In the examination, approximately 1x1 cm mass was detected
under the skin in the left medial crus of the alar cartilage. The patient
underwent mass excision from the left nasal passage under local
anesthesia. The patient had no postoperative complications. Histopathological
examination of the operation material was reported as a neurofibroma.
The aim of this case report is discuss case in light of
literature in the terms of symptoms, diagnosis and surgical methods.
Keywords: Neurofibroma; nasal cavity; peripheral nerve sheath tumor
ÖZET
Periferik sinir kılıfı tümörlerinin çoğu benigndir. Periferik sinir
kılıfı tümörlerinden olan nörofibroma nazal kavitede nadiren görülmektedir.
Nörofibromun kesin tanısı; spesimenin histopatolojik inceleme
sonucuyla konulabilir. 46 yaşında kadın hasta, uzun senelerdir sol
nazal kavite girişinde yavaş bir şekilde büyüme gösteren kitle şikayeti
ile Fatih Sultan Mehmet Eğitim ve Araştırma Hastanesi Kulak Burun
Boğaz polikliniğine başvurdu. Hastanın preoperatif muayenesinde
solda alar kartilaj medial yüzü üzerinde cilt altında yaklaşık 1x1 cm
boyutlarında kitle tespit edildi. Hastaya lokal anestezi altında sol nazal
pasajdan kitle eksizyonu operasyonu yapıldı. Hastanın postoperatif
komplikasyonu olmadı. Operasyon materyalinin histopatolojik inceleme
sonucu nörofibrom olarak raporlandı. Ameliyat spesmenin histopatolojik
sonucu; nörofibrom gelmiştir. Bu bildirinin amacı; olgunun
semptom, tanı ve tercih edilecek cerrahi yöntemleri açısından literatür
ışığında tartışılmasıdır.
Anahtar Kelimeler: Nörofibrom; nazal kavite; periferik sinir kılıfı tümörü
KAYNAKLAR
- Canda MS. [Peripheral nerve sheath tumors]. Türkiye Ekopatoloji Dergisi. 2004;10(1-2):65-74. [Link]
- Mondal AR, Rashid MA, Bera SP, Roy S. Neurofibroma of paranasal sinuses - a case report. Indian J Otolaryngol Head Neck Surg. 2004;56(1):40-2. [Crossref] [PubMed] [PMC]
- Ohashi R, Wakayama N, Kawamoto M, Tsuchiya S, Okubo K. Solitary nasal schwannoma: Usefulness of CD34 and calretinin staining for distinction from histological mimics. J Nippon Med Sch. 2013;80(4):300-6. [Crossref] [PubMed]
- Gökçeer T, Yaylaci A, Akkaynak AC, Peker O, Karaaslan O. [Nasal schwannoma: a report of two cases]. Kulak Burun Bogaz Ihtis Derg. 2004;13(1-2):46-50. Turkish. [PubMed]
- Azani AB, Bishop JA, Thompson LD. Sinonasal tract neurofibroma: a clinicopathologic series of 12 cases with a review of the literature. Head Neck Pathol. 2015;9(3):323-33. [Crossref] [PubMed] [PMC]
- Sharma DK, Sohal BS, Parmar TL, Arora H. Schwannomas of head and neck and review of literature. Indian J Otolaryngol Head Neck Surg. 2012;64(2): 177-80. [Crossref] [PubMed] [PMC]
- Ada E. [Imaging in Diagnosis and Follow-up in Sinonazal Neoplasia]. Trd Sem 2018; 6: 380-95. [Crossref]
- Min HJ, Kim KS. Differential diagnosis between nasal septal schwannoma and nasal septal neurofibroma. J Craniofac Surg. 2017;28(7):1780-3. [Crossref] [PubMed]
- Biswas D, Mal R. Bilateral solitary maxillary sinus neurofibroma. Ear Nose Throat J. 2010;89(1):E1-2. [Crossref] [PubMed]
- Rokutanda S, Yamada SI, Kawasaki G, Kawano T, Yanamoto S, Fujita S, et al. Solitary neu rofibroma of the maxillary sinus: report of a case. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2012;24(3):171-4. [Crossref]
- Kuroda N, Kazakov DV, Hes O, Michal M, Goda M, Miyazaki K, et al. Hybrid peripheral nerve sheath tumor of the nasal cavity showing sch wannomatous, neurofibromatous, and perineuriomatous areas. Med Mol Morphol. 2010;43(2): 82-5. [Crossref] [PubMed]