ORIGINAL RESEARCH
Normative Values of Cervical and Ocular Vestibular Myogenic Potentials in Young Adults
Genç Erişkinlerde Servikal ve Oküler Vestibüler Uyarılmış Miyojenik Potansiyellerin Normatif Değerleri
Received Date : 24 Jul 2020
Accepted Date : 18 Oct 2020
Available Online : 23 Dec 2020
Hatice Sema BAŞAKa, Osman TIĞb, Yaşar Can AKARa, Aylin ERYILMAZa
aAydın Adnan Menderes Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları ve Baş Boyun Cerrahisi ABD, Aydın, TÜRKİYE
bAydın Adnan Menderes Üniversitesi Tıp Fakültesi, Odyoloji BD, Aydın, TÜRKİYE
Doi: 10.24179/kbbbbc.2020-78240 - Makale Dili: TR
KBB ve BBC Dergisi. 2020;28(3):247-54
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: This study was carried out in order to obtain
normal data of our device and our application so that the Vestibular
Evoked Myogenic Potentials (VEMP) test can take its place in the test
battery we use in the dizziness / balance laboratory. Material and
Methods: Individuals without vestibular pathology were included in
the study according to the Vertigo Dizziness Imbalance Symptom Scale
and Vertigo Dizziness Imbalance Quality of Life forms. Cervical
(cVEMP) and ocular (oVEMP) tests, P1 latency, N1 latency P1-N1 amplitude,
P1-N1 interpeak interval (IPI), P1-N1 interaural amplitude
asymmetry ratio (IAAO) and VEMP response were evaluated. The obtained
parameters were compared in terms of gender and right / left ear
differences. Results: A total of 56 people, 20 (37.7%) female and 36
(64.3%) male, were included in the study. The age range was between
17-29 (23.32±1.62). In terms of the parameters evaluated, there was no
difference between genders in sVEMP and oVEMP parameters. When
the right and left ears were compared, no significant difference was
found in terms of P1 latency, N1 latency, P1-N1 IPI values in the whole
study group, but a statistically significant difference was found in the
amplitude of P1-N1. In the cervical VEMP test, in 112 ears the results
are as; P1 latency 14.16 ms (±2.45), N1 latency 21.44 ms (±2.67), P1-
N1 IPI 7.28 ms (±2.07), P1-N1 Amplitude 197.14 μV (±133.60) and
P1-N1 IAAO 11.95 (±28.76). In ocular VEMP, P1 latency is 14.71 ms
(±1.04), N1 latency is 9.99 ms (±0.42), P1-N1 IPI is 4.71 ms (±0.96)
and P1-N1 amplitude value was found as 8.08 μV (±6.05). Conclucion:
With this study, normative values of our clinic in healthy young
adult age group were obtained for sVEMP and oVEMP tests that we
use in routine diagnosis. Our results will guide us in the evaluation of
patients with vestibular pathology.
Keywords: Normative; cVEMP; oVEMP
ÖZET
Amaç: Bu çalışma, vestibüler uyarılmış miyojenik potansiyeller
[vestibular evoked myogenic potentials (VEMP)] testinin, baş dönmesi/
denge laboratuvarında kullandığımız test bataryası içinde yerini
güçlü bir şekilde alabilmesi için cihazımıza ve uygulamamıza ait normal
verileri elde etmek amacı ile yapılmıştır. Gereç ve Yöntemler: Çalışmaya
“Vertigo Dizziness Imbalance Semptom Skalası ve Vertigo
Dizziness Imbalance Yaşam Kalitesi” formlarına göre vestibüler patoloji
düşünülmeyen kişiler dâhil edildi. Servikal (sVEMP) ve oküler
(oVEMP) testleri, P1 latansı, N1 latansı, P1-N1 amplitüdü, P1-N1 interpik
intervali (İPİ), P1- N1interaural amplitüd asimetri oranı (İAAO)
ve VEMP yanıtı alıp almama açısından değerlendirildi. Elde edilen parametreler,
cinsiyet ve sağ/sol kulak farkları açısından karşılaştırıldı.
Bulgular: Çalışmaya 20 (%37,7) kadın, 36 (%64,3) erkek olmak üzere
toplam 56 kişi dâhil edildi. Yaş aralığı 17-29 (23,32±1,62) arasındaydı.
Değerlendirilen parametreler açısından, sVEMP ve oVEMP parametrelerinde
cinsiyetler arasında fark bulunmadı. Tüm çalışma grubunda
sağ ve sol kulaklar karşılaştırıldığında P1 latans, N1 latans, P1-N1 İPİ
değerleri açısından anlamlı bir fark bulunmamıştır, ancak P1-N1 amplitüd
değerinde istatistiksel olarak anlamlı fark saptanmıştır. sVEMP
testinde 112 kulakta P1 latans 14,16 ms (±2,45), N1 latans 21,44 ms
(±2,67) ve P1-N1 İPİ 7,28 ms (±2,07), P1-N1 amplitüd 197,14 μV
(±133,60) ve P1-N1 İAAO 11,95 (±28,76) olarak elde edilmiştir.
oVEMP’te P1 latans 14,71 ms (±1,04), N1 latans 9,99 ms (±0,42), P1-
N1 İPİ 4,71 ms (±0,96) ve P1-N1 amplitüd değeri ise 8,08 μV (±6,05)
olarak bulunmuştur. Sonuç: Bu çalışma ile rutin tanıda kullandığımız
sVEMP ve oVEMP testleri için sağlıklı genç erişkin yaş grubunda kliniğimizin
normatif değerleri elde edilmiştir. Sonuçlarımız vestibüler
patolojisi olan hastaların değerlendirilmesinde bize yol gösterecektir.
Anahtar Kelimeler: Normatif; sVEMP; oVEMP
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