CASE REPORTS
Rare Pathology of the Larynx: Papillary Oncocytic Cystadenoma Case Report
Larenksin Nadir Görülen Patolojisi: Papiller Onkositik Kistadenoma Olgu Sunumu
Received Date : 07 Dec 2020
Accepted Date : 21 Jan 2021
Available Online : 23 Mar 2021
Hüseyin Avni ULUSOYa, Filiz GÜLÜSTANa
aClinic of Otorhinolaryngology, Division of Audiology, İstanbul Dr. Sadi Konuk Training and Research Hospital, İstanbul, TURKEY
Doi: 10.24179/kbbbbc.2020-80454 - Makale Dili: EN
KBB ve BBC Dergisi. 2021;29(2):148-51
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Laryngeal cystadenoma (other terminological names; oncocytic
cystadenoma, papillary cystadenoma, oncocytic adenoma) is a
rare benign, slow growing, predominantly composed of oncocytes and
its epithelial component is similar to Warthin tumors (papillary cystadenoma
lymphomatosum) seen in the major salivary glands. We
aimed to present the rare case of laryngeal oncocytic cystadenoma in
the same case by examining the relationship between the accompanying
parotid gland's Warthin tumor. Laryngeal oncocytic cysts are histologically
similar to Warthin (papillary cystadenoma lymphomatosum)
tumor, but differentiate due to the fact that it does not have a two-fold
structure consisting of oncocyte and lymphoid stroma is similar to that.
Magnetic resonance imaging is the gold standard method in diagnosis
of complex lesions. The optimal treatment is endoscopic or open laryngeal
surgical excision. Malignant transformation of the lesion is not
clear, close monitoring of the operated area is essential.
Keywords: Laryngeal diseases; systadenoma; adenolymphoma
ÖZET
Laringeal kistadenomlar (diğer terminolojik isimler; onkositik
kistadenom, papiller kistadenom, onkositik adenom), nadir görülen benign,
yavaş büyüyen ve ağırlıklı olarak onkositlerden oluşur. Epitelyal
patolojisi, majör tükürük bezlerinde görülen Warthin tümörlerine (papiller
kistadenoma lenfomatozum) benzerdir. Nadir görülen laringeal
onkositik kistadenomu olgusunun, aynı olguda ona eşlik eden parotis
bezinin Warthin tümörü ile ilişkisini incelemeyi amaçladık. Laringeal
onkositik kistler, histolojik olarak Warthin (papiller kistadenoma lenfomatozum)
tümörüne benzer, ancak onkosit ve lenfoid stromadan oluşan
2 katlı yapısı olmaması nedeniyle ayrışmaktadır. Manyetik
rezonans görüntüleme yöntemi, kompleks lezyonların tanısında altın
standart tanı yöntemidir. En uygun tedavi, endoskopik veya açık laringeal
cerrahi eksizyondur. Lezyonun maligniteye dönüşümü ile ilgili bilgiler
net olmadığından ameliyat edilen bölgenin yakından izlenmesi
şarttır.
Anahtar Kelimeler: Larinks hastalıkları; kistadenom; adenolenfoma
KAYNAKLAR
- DeSanto LW, Devine KD, Weiland LH. Cysts of the larynx--classification. Laryngoscope. 1970;80(1):145-76. [Crossref] [PubMed]
- Newman BH, Taxy JB, Laker HI. Laryngeal cysts in adults: a clinicopathologic study of 20 cases. Am J Clin Pathol. 1984;81(6):715-20. [Crossref] [PubMed]
- Nisa L, Landis BN, Salmina C, Ailianou A, Karamitopoulou E, Giger R. Warthin's tumor of the larynx: a very rare case and systematic review of the literature. J Otolaryngol Head Neck Surg. 2015;44(1):16. [Crossref] [PubMed] [PMC]
- Allegra SR. Warthin's tumor: a hypersensitivity disease? Ultrastructural, light, and immunofluorescent study. Hum Pathol. 1971;2(3):403-20. [Crossref] [PubMed]
- Stenner M, Müller KM, Koopmann M, Rudack C. Squamous cell carcinoma of the larynx arising in multifocal pharyngolaryngeal oncocytic papillary cystadenoma: a case report and review of the literature. Medicine (Baltimore). 2014;93(12):e70. [Crossref] [PubMed] [PMC]
- Salerno G, Mignogna C, Cavaliere M, D'Angelo L, Galli V. Oncocytic cyst of the larynx: an unusual occurrence. Acta Otorhinolaryngol Ital. 2007;27(4):212-5. [PubMed] [PMC]
- Brandwein M, Huvos A. Laryngeal oncocytic cystadenomas. Eight cases and a literature review. Arch Otolaryngol Head Neck Surg. 1995;121(11):1302-5. [Crossref] [PubMed]
- Feinstein AJ, Peng KA, Bhuta SM, Abemayor E, Mendelsohn AH. Laryngeal oncocytic cystadenomas masquerading as laryngoceles. Am J Otolaryngol. 2016;37(1):17-21. [Crossref] [PubMed]
- Puttasiddaiah PM, Berry S, Whittet HB, Kumar M. Laryngeal oncocytic cyst presenting with an acute onset of stridor. Ear Nose Throat J. 2009;88(7):1003-4. [Crossref] [PubMed]
- Baird S, Mann H, Salinas-La Rosa CM, Ozdemir H. Oncocytic cyst of the larynx: a rare finding. BMJ Case Rep. 2019;12(1):bcr-2018-227214. [Crossref] [PubMed] [PMC]
- Heyes R, Lott DG. Laryngeal cysts in adults: simplifying classification and management. Otolaryngol Head Neck Surg. 2017;157(6):928-39. [Crossref] [PubMed]
- Martin-Hirsch DP, Lannigan FJ, Irani B, Batman P. Oncocytic papillary cystadenomatosis of the larynx. J Laryngol Otol. 1992;106(7):656-8. [Crossref] [PubMed]
- Sinacori JT, Jack RA 2nd, Workman JR. Rapid growth of a laryngeal oncocytic cyst after surgical irritation. Ear Nose Throat J. 2014;93(10-11):E44-5. [Crossref] [PubMed]
- Tsai YT, Lee LA, Fang TJ, Li HY. Treatment of vallecular cysts in infants with and without coexisting laryngomalacia using endoscopic laser marsupialization: fifteen-year experience at a single-center. Int J Pediatr Otorhinolaryngol. 2013;77(3):424-8. [Crossref] [PubMed]
- Lisan Q, Hoffmann C, Jouffroy T, Hans S. Combined laser and robotic approach for the management of a mixed laryngomucocele. J Robot Surg. 2016;10(1):81-3. [Crossref] [PubMed]