ORIGINAL RESEARCH
Ekstrakraniyal Baş Boyun Schwannomlarının Cerrahi ve Klinik Sonuçları: 45 Hastanın Analizi
Surgical and Clinical Results of Extracranial Head and Neck Schwannomas: Analysis of 45 Patients
Received Date : 04 Mar 2025
Accepted Date : 07 Apr 2025
Available Online : 29 Apr 2025
Mehmet Ekrem ZORLUa, Mehmet Barış OKUMUŞa, Muammer Melih ŞAHİNa, Metin Emin DEMİRKANa, Betül ÖĞÜTb, Mehmet DÜZLÜa, Utku AYDİLa
aGazi University Faculty of Medicine, Department of Ear Nose and Throat Diseases, Ankara, Türkiye bGazi University Faculty of Medicine, Department of Pathology, Ankara, Türkiye
Doi: 10.24179/kbbbbc.2025-110132 - Makale Dili: EN
Journal of Ear Nose Throat and Head Neck Surgery. 2025;33(3):106-14.
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: The aim of this study was to retrospectively
analyze the clinical and demographic characteristics, presenting symptoms,
postoperative complications, nerve of origin, and location of
schwannomas in patients operated for extracranial head and neck
schwannomas. Material and Methods: Patients who underwent
surgery for extracranial nonvestibular head and neck schwannomas between
January 2008-August 2024 at the Gazi University Department of
Ear Nose and Throat were included in the study. Clinical and demographic
characteristics, presenting symptoms, tumor location and size,
preoperative imaging and biopsy results, nerve of origin of the schwannoma,
types of surgical procedures, postoperative complications, and
follow-up findings were retrospectively analyzed. Results: The study
included 45 patients. 14 (31.1%) of the patients were male and 31
(68.8%) were female, and the mean age was 39.08 years (9-82 years).
The most common localization was the parapharyngeal region in 12
patients (26.6%). In 31 patients (68.9%), the nerve of origin could be
identified before or during surgery. The nerve of origin was the vagus
nerve in 11 patients (24.4%), facial nerve in 9 patients (20.4%), brachial
plexus in 4 patients (8.8%), sympathetic trunk in 3 patients (6.6%), and
cervical plexus in 2 patients (4.4%). Of the 40 patients in whom the
tumor was excised, 17 (42.5%) had postoperative neurological deficit
in the nerve of origin after surgery. Conclusion: Schwannomas are usually
asymptomatic and slow-growing tumors but may lead to significant
morbidity. Although surgery is the definitive treatment, there are different
treatment options available considering asymptomatic patients.
Patients should be informed that neurological deficits may occur after
surgery.
Keywords: Cranial nerves; head and neck tumors; schwannomas
ÖZET
Amaç: Bu çalışmada, ekstrakraniyal baş boyun schwannomu
nedeniyle opere edilen hastaların klinik ve demografik özellikleri, başvuru
semptomları, operasyon sonrası komplikasyonları, schwannomun
köken aldığı sinir ve yerleşim yerlerinin geriye dönük olarak analiz
edilmesi amaçlanmıştır. Gereç ve Yöntemler: Gazi Üniversitesi Kulak
Burun Boğaz Ana bilim Dalı’nda Ocak 2008-Ağustos 2024 yılları arasında
ekstrakraniyal nonvestibüler baş ve boyun schwannomu nedeniyle
opere edilen hastalar çalışmaya dâhil edildi. Hastaların klinik ve
demografik özellikleri, başvuru semptomları, tümör lokasyon ve boyutları,
operasyon öncesi görüntüleme ve biyopsi sonuçları, schwannomun
köken aldığı sinir, cerrahi prosedür tipleri, postoperatif
komplikasyonlar ve takip bulguları retrospektif olarak analiz edildi.
Bulgular: Çalışmaya 45 hasta dâhil edildi. Hastaların 14’ü (%31,1)
erkek, 31’i (%68,8) kadın olup ortalama yaş 39,08 (9-82 yaş) olarak
saptandı. En sık yerleşim yeri olarak 12 hastada (%26,6) parafarengeal
bölge tespit edildi. 31 hastada (%68,8) tümörün köken aldığı sinir cerrahi
öncesinde veya operasyon sırasında belirlenebildi. Kitlenin kaynaklandığı
sinir 11 hastada (%24,4) 10. kraniyal sinir, 9 hastada
(%20,4) 7. kraniyal sinir, 4 hastada (%8,8) brakial pleksus, 3 hastada
(%6,6) servikal sempatik zincir, 2 hastada (%4,4) hastada servikal pleksus
kökenli olarak izlendi. Tümörün eksize edildiği 40 hastanın
17’sinde (%42,5) cerrahi sonrası ilgili sinirde nörolojik defisit saptandı.
Sonuç: Schwannomların çoğunlukla asemptomatik ve yavaş büyüyen
tümörler olmalarına rağmen önemli morbiditelere sebep olabilirler. Cerrahi
kesin tedavi olmakla birlikte asemptomatik hastalar da göz önünde
bulundurulduğunda farklı tedavi seçenekleri bulunmaktadır. Cerrahi
sonrası nörolojik defisitlerin gelişebileceği hastayla paylaşılmalıdır.
Anahtar Kelimeler: Kraniyal sinirler; baş boyun tümörleri; schwannomalar
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