ORIGINAL RESEARCH
Evaluation of Coroid Thickness of Patients with Nazal Polype
Nazal Polipi Olan Hastaların Koroid Kalınlığının Değerlendirilmesi
Received Date : 12 Apr 2020
Accepted Date : 18 May 2020
Available Online : 30 Oct 2020
Emine SAVRAN ELİBOLa, Remzi DOĞANb, Ahmet ELBAYc, Ahmet Adnan CIRIKd,
Veysel AYKUTe, Alper YENİGÜNb
aGöztepe Eğitim ve Araştırma Hastanesi, Göz Hastalıkları ABD, İstanbul, TÜRKİYE
bBezmialem Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları ABD, İstanbul, TÜRKİYE
cBezmialem Vakıf Üniversitesi Tıp Fakültesi, Göz Hastalıkları ABD, İstanbul, TÜRKİYE
dÜmraniye Eğitim ve Araştırma Hastanesi, Kulak Burun Boğaz Hastalıkları ABD, İstanbul, TÜRKİYE
eİstanbul Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi, Göz Hastalıkları ABD, İstanbul, TÜRKİYE
bBezmialem Vakıf Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları ABD, İstanbul, TÜRKİYE
Doi: 10.24179/kbbbbc.2020-75404 - Makale Dili: TR
KBB ve BBC Dergisi. 2020;28(3):216-21
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: Comparison of choroid thicknesses of patients
with nasal polyp with control group of healthy individuals. Material
and Methods: A total of 65 patients, 32 patients with nasal polyp
and 33 healthy individuals, were included in the study. Choroidal thickness
was measured with Spectralis® OCT (software version 5.3, Heidelberg
Engineering, Heidelberg, Germany) without dilating the pupil.
Measurements were taken from the subfovea and the nasal and temporal
points at a distance of 1.500 μm from the fovea central. Results:
There was no difference between the 2 groups in terms of age and gender
(Group 1: p=0.613 and Group 2: p=0.342). The mean subfoveal
choroid thickness was 322.31±75.89 in patients with nasal polyp, while
it was 397.15±78.70 in the control group. No statistically significant
difference was found (p=0.194). Conclusion: In our study, no significant
difference was found in the comparison of choroidal thickness
measurement of patients with nasal polyp and healthy volunteers.
Keywords: Nasal polyp; choroid; optical coherence tomography; allergic rhinitis
ÖZET
Amaç: Nazal polipi olan hastaların koroid kalınlıklarının sağlıklı
bireylerden oluşan kontrol grubuyla karşılaştırılması. Gereç ve
Yöntemler: Çalışmaya, nazal polipi olan 32 hasta ve 33 sağlıklı birey
olmak üzere toplam 65 hasta dâhil edildi. Koroid kalınlığı pupil dilate
edilmeden Spectralis® OCT (software version 5.3, Heidelberg Engineering,
Heidelberg, Almanya) cihazı ile ölçüldü. Fovea santralinden ve
fovea santraline 1.500 μm mesafedeki nazal ile temporal noktalardan
ölçümler alındı. Bulgular: Ortalama yaş ve cinsiyet açısından 2 grup
arasında fark bulunmadı (Grup 1: p=0,613 ve Grup 2: p=0,324). Ortalama
subfoveal koroid kalınlığı nazal polipi olan hastalarda
322,31±75,89 iken kontrol grubunda 397,15±78,70 idi. İstatistiksel olarak
anlamlı bir fark bulunamadı (p=0,194). Sonuç: Çalışmamızda,
nazal polipi olan hastalarla sağlıklı gönüllü hastaların koroid kalınlık ölçümünün
karşılaştırmasında anlamlı fark bulunamamıştır.
Anahtar Kelimeler: Nazal polip; koroid; optik koherens tomografi; alerjik rinit
KAYNAKLAR
- Nicholson B, Noble J, Forooghian F, Meyerle C. Central serous chorioretinopathy: update on pathophysiology and treatment. Surv Ophthalmol. 2013;58(2):103-26.[Crossref] [PubMed] [PMC]
- Bouzas EA, Karadimas P, Pournaras CJ. Central serous chorioretinopathy and glucocorticoids. Surv Ophthalmol. 2002;47(5):431-48.[Crossref] [PubMed]
- Mirza RG, Gill M. Central serous chorioretinopathy associated with unusual routes of steroid administration. Retin Cases Brief Rep. 2009;3(1):99-101.[Crossref] [PubMed]
- Yannuzzi LA. Central serous chorioretinopathy: a personal perspective. American J Ophthalmol. 2010149(3):361-3.[Crossref] [PubMed]
- Imamura Y, Fujiwara T, Margolis R, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy. Retina. 2009;29(10):1469-73.[Crossref] [PubMed]
- Yenigun A, Elbay A, Dogan R, Ozturan O, Ozdemir MH. The effect of allergic rhinitis with positive skin prick test on choroidal thickness. Eur Arch Otorhinolaryngol. 2017;274(6):2477-81.[Crossref] [PubMed]
- Ulaş F, Doğan Ü, Çelik F, Soydan A, Çelebi S, Dikbaş OJJoR-V. Evaluation of retinal, retinal nerve fiber layer and choroidal thicknesses in diabetic patients without diabetic retinopathy. Journal of Retina Vitreus. 2015;23(4):331-5.
- Ulaş F, Dogan Ü, Dikbas O, Celebi S, Keles A. Investigation of the choroidal thickness in patients with hypothyroidism. Indian J Ophthalmol. 2015;63(3):244-9.[Crossref] [PubMed] [PMC]
- Akay F, Genç H, Kumbul YÇ. Effect of the inflammatory bowel diseases on choroidal and macular thickness. Med J SDU. 2018;25(3):317-21.
- Elbay A, Yenigün A, Özdemir H, Çalım ÖF, Ekinci C, Çetinkaya R, et al. [Does corticosteroid nasal spray use play a role in development of central serous chorioretinopathy?]. Anatol Clin. 2017;22(3):163-8.[Crossref]
- Katırcıoğlu OS. [Nasal polyposis: decription and history, prevalence, ethiopatho-genesis, clinical, diagnosis and physical exam, treatment]. Turkiye Klinikleri J Surg Med Sci. 2006;2(23):8-15.
- Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol. 2008;146(4):496-500.[Crossref] [PubMed]
- Margolis R, Spaide RF. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. Am J Ophthalmol. 2009;147(5):811-5.[Crossref] [PubMed]
- Manjunath V, Taha M, Fujimoto JG, Duker JS. Choroidal thickness in normal eyes measured using Cirrus HD optical coherence tomography. Am J Ophthalmol. 2010;150(3):325-9.e1.[Crossref] [PubMed] [PMC]
- Wei WB, Xu L, Jonas JB, Shao L, Du KF, Wang S, et al. Subfoveal choroidal thickness: the Beijing eye study. Ophthalmology. 2013;120(1):175-80.[Crossref] [PubMed]
- Usui S, Ikuno Y, Akiba M, Maruko I, Sekiryu T, Nishida K, et al. Circadian changes in subfoveal choroidal thickness and the relationship with circulatory factors in healthy subjects. Invest Ophthalmol Vis Sci. 2012;24;53(4):2300-7.[Crossref] [PubMed]
- Tan CS, Ouyang Y, Ruiz H, Sadda SVR. Diurnal variation of choroidal thickness in normal, healthy subjects measured by spectral domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2012;25;53(1):261-6.[Crossref] [PubMed]
- Shinojima A, Iwasaki KI, Aoki K, Ogawa Y, Yanagida R, Yuzawa M, et al. Subfoveal choroidal thickness and foveal retinal thickness during head-down tilt. Aviat Space Environ Med. 2012;83(4):388-93.[Crossref] [PubMed]
- Zengin MÖ, Karahan E, Özyurtlu F, Tuncer İ, Pekel N, Çınar E, et al. The effect of blood pressure regulation on choroidal thickness. Ret-Vit. 2014;22(3):213-6.
- Nickla DL, Wallman J. The multifunctional choroid. Prog Retin Eye Res. 2010;29(2):144-68.[Crossref] [PubMed] [PMC]
- Matsuoka M, Ogata N, Otsuji T, Nishimura T, Takahashi K, Matsumura M, et al. Expression of pigment epithelium derived factor and vascular endothelial growth factor in choroidal neovascular membranes and polypoidal choroidal vasculopathy. Br J Ophthalmol. 2004;88(6):809-15.[Crossref] [PubMed] [PMC]
- Maruko I, Iida T, Sugano Y, Oyamada H, Sekiryu T, Fujiwara T, et al. Subfoveal choroidal thickness after treatment of Vogt-Koyanagi-Harada disease. Retina. 2011;31(3):510-7.[Crossref] [PubMed]
- Shatkin JS, Delsupehe KG, Thisted RA, Corey JP. Mucosal allergy in the absence of systemic allergy in nasal polyposis and rhinitis: a meta-analysis. Otolaryngol Head Neck Surg. 1994;111(5):553-6.[Crossref] [PubMed]
- Tapan ÖO, Tapan U, Kılıç ÜS. [Effects of hypoxia on the eye in patients with obstructive sleep apnea syndrome]. Journal of Turkish Sleep Medicine. 2016;2:43-7.
