ISSN: 1300 - 6525 E-ISSN: 2149 - 0880
kulak burun boğaz
ve baş boyun cerrahisi dergisi
http://dergi.kbb-bbc.org.tr
Koşulsuz Destek Verenler

Kayıtlı İndeksler








CASE REPORTS

Two Mucosal Malignant Melanoma Case Reports Presented During COVID-19 Pandemic
COVID-19 Pandemi Döneminde Sunulan İki Mukozal Malign Melanom Olgu Sunumu
Received Date : 08 Dec 2021
Accepted Date : 04 Apr 2022
Available Online : 13 Apr 2022
Doi: 10.24179/kbbbbc.2021-84293 - Makale Dili: EN
KBB ve BBC Dergisi. 2022;30(2):97-102
Copyright © 2020 by Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Mucosal malignant melanoma of the head and neck are fairly rare pathologies. Even if it is not macroscopically pigmented, malignant melanoma should be included in the differential diagnosis in mucosal lesions. Mucosal malignant melanoma cases which were admitted during the coronavirus disease-2019 pandemic in 2020 were retrospectively screened. Two cases were detected. The first case was a 42-year-old male patient with tonsillar malignant melanoma presenting with a nonpigmented ulcerated mass. Second case was a 56-yearold male patient with a pigmented lesion in the left pyriform sinus. In the first case, modified radical neck dissection and lobectomy for the mass in the lung were performed at different times after whole body positron emission tomography-computed tomography scanning. Lobectomy material and two metastatic lymph nodes in the neck dissection were reported as invasive malignant melanoma. In the second case, retropharyngeal lymph node metastasis was detected accompanying the primary lesion after whole body positron emission tomography scan. Both patients were referred to oncology department for adjuvant therapy after surgical excisions.
ÖZET
Baş ve boyun mukozal malign melanomları oldukça nadir görülen patolojilerdir. Makroskobik pigmentli olmasa bile malign melanom, mukozal lezyonlarda ayırıcı tanıya dâhil edilmelidir. Koronavirüs hastalığı-2019 salgını sırasında 2020 yılında başvuran mukozal malign melanom olguları retrospektif olarak tarandı. İki olgu tespit edildi. İlk olgu, pigmente olmayan ülsere kitle ile başvuran tonsiller malign melanom olan 42 yaşında bir erkek hastaydı. İkinci olgu, sol piriform sinüste pigmente lezyon bulunan 56 yaşında erkek hastaydı. İlk olguda tüm vücut pozitron emisyon tomografi-bilgisayarlı tomografi taraması sonrası farklı zamanlarda modifiye radikal boyun diseksiyonu ve akciğerdeki kitle için lobektomi yapıldı. Lobektomi materyali ve boyun diseksiyonundaki 2 metastatik lenf nodu invaziv malign melanom olarak rapor edildi. İkinci olguda pozitron emisyon tomografi-bilgisayarlı tomografi taraması sonrası primer lezyona eşlik eden retrofaringeal lenf nodu metastazı saptandı. Her iki hasta da cerrahi eksizyonlardan sonra adjuvan tedavi için onkolojiye yönlendirildi.
KAYNAKLAR
  1. McLaughlin CC, Wu XC, Jemal A, Martin HJ, Roche LM, Chen VW. Incidence of noncutaneous melanomas in the U.S. Cancer. 2005;103(5):1000-7. [Crossref]  [PubMed] 
  2. López F, Rodrigo JP, Cardesa A, Triantafyllou A, Devaney KO, Mendenhall WM, et al. Update on primary head and neck mucosal melanoma. Head Neck. 2016;38(1):147-55. [Crossref]  [PubMed]  [PMC] 
  3. Axéll T, Hedin CA. Epidemiologic study of excessive oral melanin pigmentation with special reference to the influence of tobacco habits. Scand J Dent Res. 1982;90(6):434-42. [Crossref]  [PubMed] 
  4. Hicks MJ, Flaitz CM. Oral mucosal melanoma: epidemiology and pathobiology. Oral Oncol. 2000;36(2):152-69. [Crossref]  [PubMed] 
  5. Aguas SC, Quarracino MC, Lence AN, Lanfranchi-Tizeira HE. Primary melanoma of the oral cavity: ten cases and review of 177 cases from literature. Med Oral Patol Oral Cir Bucal. 2009;14(6):E265-71. [PubMed] 
  6. Osorio M, Moubayed SP, Hernandez-Prera J, Scott JC, Urken ML. Primary mucosal melanoma of the palatine tonsil: Report of a case and review of the literature. Am J Otolaryngol. 2017;38(4):501-4. [Crossref]  [PubMed] 
  7. Eravcı FC, Arbag H, Bayrakci E, Dündar MA. [Impact of the Covid-19 pandemic on the surgical volume of otolaryngology: experience of a tertiary referral center]. KBB ve BBC Dergisi. 2021;29(2):127-35. [Crossref] 
  8. Auluck A, Zhang L, Desai R, Rosin MP. Primary malignant melanoma of maxillary gingiva--a case report and review of the literature. J Can Dent Assoc. 2008;74(4):367-71. [PubMed] 
  9. Lengyel E, Gilde K, Remenár E, Esik O. Malignant mucosal melanoma of the head and neck. Pathol Oncol Res. 2003;9(1):7-12. [Crossref]  [PubMed] 
  10. Nenclares P, Ap Dafydd D, Bagwan I, Begg D, Kerawala C, King E, et al. Head and neck mucosal melanoma: The United Kingdom national guidelines. Eur J Cancer. 2020;138:11-8. [Crossref]  [PubMed]